CED Whisker Stimulator 3901

Controls an array of piezo-electric stimulator elements

The CED 3901 whisker stimulator is a controller for an array of piezo-electric stimulator elements, offering precisely controlled temporal patterns, with repeatable stimulation. Each 3901 drives 9 stimulator elements and up to 7 can be linked, to control up to 63 elements.

It is mains-powered and is controlled by 8 bits of the digital output of a CED 1401, or by USB. Each of the stimulator elements can be connected to one of four sources; either of the two external waveform inputs, an individual programmable pseudo-random noise generator, or mute.

Software control is provided as a demonstration Spike2 script.

  • Precisely control temporal patterns with repeatable stimulation
  • Horizontal, vertical and diagonal control
  • 9 to 63 output channels ±45v @ 10mA
  • Drive grids of 3×3 up to 7×9
  • Filtered outputs 2nd order low pass Butterworth (1kHz)
  • Output muting
  • Independent pseudo random noise generators
  • Adjustable noise levels
  • Use with Micro or Power intelligent interface or driven from other DAQ system
  • Software controlled – USB or 8-bit digital communication
  • Size – Micro1401 format: 366 x 48 x 217mm (14.4 x 1.75 x 8.5 ins) (W x H x D)

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CED 4001-16 Mains Pulser

The CED 4001-16 Mains Pulser generates mains-frequency-locked pulses that can be used to reduce the magnitude of mains pickup (‘hum’) in recorded signals. The output is on a BNC connector, double-isolated from mains and consists of a train of 150 microsecond positive-going 5V TTL pulses, suitable for direct connection to a 1401 Event input.

The Mains Pulser will run off any mains supply between 100 -240 V AC, 50 – 60 Hz. The case is earthed to mains earth. Current consumption is less than 100 mA.

Box size: 104mm x 126mm x 53mm (W x D x H).

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CED 4003 Potentiometer

The CED 4003 is a simple linear 10k potentiometer, intended to provide manually adjustable signal division. It is cased and has BNC leads that allow input connection from a voltage source such as a 1401 DAC waveform output, with an output connection suitable for an ADC waveform input.

The potentiometer output is controlled by a slider, with markings and writeable labels.

Case size: 166mm x 70mm x 28mm, lead length 2 metres.

The input voltage should not exceed 30V.

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CED 3505 Programmable Attenuator

The CED 3505 and 3505HP are single-channel programmable attenuators offering main attenuations from 0dB to over 100dB in 2.5, 3 or 5dB steps.

Control of the attenuation and other programmable features of the 3505 is via an internal USB-serial port. It may be controlled by scripts in Spike2 or Signal. Fast attenuation changes may also be implemented via a parallel port designed to interface with a CED1401 digital output. In this way, the sequencer facility in the CED Spike2 software package can control the attenuation for real-time synchronisation under experimental conditions.

The standard 3505 has an additional output connector producing an “attenuation changed” pulse. The jack socket carries the output from an internal audiometric headphone amplifier, designed to drive standard audiometric headphones to sound pressure levels of around 140dB. The attenuator output signal can be routed to one or both headphones, and there is an independent calibration attenuator for each headphone channel.

3505 programmable-attenuator front

3505 programmable-attenuator rear

 

Box size: 240mm x 240mm x 46mm (W x D x H), external mains-driven power supply.

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Owners Handbook

 

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CED 2502SA

Skin Conductance Unit

The 2502SA stand-alone skin conductance unit is designed to take direct measurements of the conductivity between two skin electrodes by maintaining a 500mv DC potential across them, and then measuring the current needed to maintain this potential. This current value is then represented and output as a scaled voltage, suitable for connection to a CED 1401 laboratory interface.

The 2502SA uses the constant-voltage principle and has manually switched conductance ranges of 10, 25 and 100 micromhos. The sockets accept 1.5 or 2 mm plugs.

The CED 2502SA is offered as research equipment and is not sold as a medical device within the meaning of the European Medical Device Directive.

2502SA CED Skin Conductance Unit

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CED Power1401-3A

High-performance data acquisition interface

The Power1401-3A is our latest high-performance data acquisition interface. It uses advanced processor technology to give you all the power and flexibility you need in a state-of-the-art laboratory interface.

Fast data acquisition and analysis

The Power1401-3A records waveform data, digital (event) and marker information, and can generate waveform and digital outputs simultaneously for real-time, multi-tasking experiment control. The Power1401 has a 1 GHz Marvell processor (essentially an ARM V5TE core) and up to 2GB of on-board memory, to facilitate high speed data capture, independent waveform sample rates and complex on-line analysis, freeing valuable time for the host computer to perform other tasks, such as data manipulation and further analysis.

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AlgoMed

Pressure Algometer

The AlgoMed is the first software-based computerized Pressure Algometer to offer real-time visual & auditory feedback to control & monitor applied pressure rates to measure pressure pain threshold.
Algometers are designed to quantify and document levels of tenderness via pressure pain threshold measurement and pain sensitivity via pressure pain tolerance measurement. Pressure algometry is a reliable measure of pain in muscles, fascia, joints, tendons, ligaments and the periosteum.
The challenge in performing pressure algometry tests is to apply continuously ascending pressure at a constant rate on the patient’s selected body site without having the possibility to monitor it in real time.

Features:

  • Real-time visual & auditory feedback
  • Comprehensive test statistics
  • Body site selection
  • Customizable outcome-based color graphic reports
  • Adjustable protocols, including thresholds and Ramp & hold

AlgoMed_Medoc

 

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Medoc Quantitative Sensory Testing –  Solutions for Neurophysiology

 

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Q- Sense

Simple, validated, thermal testing for small peripheral nerve fibers

Q-Sense is a portable, easy-to-use and affordable quantitative sensory testing (QST) device for clinical, research and pharmacologic trial use. Q-Sense offers scientifically validated measures of warm, cool and heat-pain thermal sensory thresholds. All of these can be useful determinants in the evaluation of peripheral sensory nerve function, neuropathic pain, diabetic, chemotherapeutic, and other small-fiber neuropathies.

Key features:

  • Sensitive and reproducible
  • Pre-programmed test algorithms
  • Versatile patient database
  • Normative reference data
  • Easy-to-interpret clinical test report
  • Easy data export to excel

Q-Sense Medoc

Q-Sense-thermode

Q-sense Symbiotic Devices

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Medoc Q-Sense Product Brochure

Medoc Quantitative Sensory Testing –  Solutions for Neurophysiology

Medoc TSA2, Q-Sense and TSA-Air2 Comparison flyer

 

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NeuroConn DC-STIMULATOR MR

Stimulator for Neuroscientific Research

The DC-STIMULATOR MR is an fMRI-compatible stimulator for use in scientific research. It is an extension of our single-channel DC-STIMULATOR PLUS, so it benefits from multi-stage monitoring and complete range of tES modes of operation: transcranial direct current simulation (tDCS), transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS).

The DC-STIMULATOR MR allows to apply transcranial electrical stimulation (tES) during functional magnetic resonance imaging (fMRI) to localize the exact position of cortical activation.

Features:

  • 1 channel, unipolar (DC) and bipolar (AC) stimulation
  • Adjustable range of current ±4,500 µA, maximum adjustable current strength ±1,500 µA (peak-to-peak)
  • Adjustable application time up to 30 minutes
  • Frequencies adjustable up to 250 Hz, phase freely adjustable
  • 4 standard modes – single (continuous stimulation) – pulse (cyclical stimulation activation/deactivation) – sinus (sinus wave) – noise (normally distributed)
  • Use during fMRI, no interference of the MRI images during EPI sequence
  • RF filter module with MRI-compatible cables and electrodes
  • Customer-specific programs possible (optional)
  • “Study mode” for blind processing of genuine and ‘pseudo’ stimulation (optional)
  • External trigger input and output (optional)

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NeuroConn DC-STIMULATOR MR Brochure

DC-STIMULATOR MR AppNote Single Channel fMRI-tES

DC-STIMULATOR MR AppNote Dual Channel fMRI-tES

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NeuroConn DC-STIMULATOR

DC Stimulator for cranial electrotherapy and neuroscientific research

The DC-STIMULATOR is a stimulator for cranial electrotherapy that provides a stimulation using weak direct current (transcranial Direct Current Stimulation tDCS) within non-invasive interventional neurophysiology. The electrical charge and current density applied are far below the threshold for releasing a stimulus and have a modular effect on existing neuronal elements.

Depending on the duration, used current, current density and frequency, the stimulation is effective on inhibiting or activating cortical activity.

The DC-STIMULATOR is used for transcranial Direct Current Stimulation for symptom relief in depression.

NeuroConn stimulators offer CE-certification and TGA certification, multi-stage monitoring and complete range of tES modes of operation:
tDCS – trans-cranial direct current stimulation
tACS – trans-cranial alternating current stimulation
tRNS – trans-cranial random noise stimulation

These currents influence neurotransmitter channels by changing the electrical charge in nerve cell membranes. In turn this changes the excitability of brain cells.

Studies have shown that tDCS can be used as a therapy method for various brain disorders that would otherwise be treated with therapeutic drugs, often associated with harmful side effects.

The NeuroConn DC stimulator and NeuroConn DC Plus offer 1 channel (anodal and cathodal) trans-cranial stimulation, adjustable application time of up to 30min with adjustable current up to 4.5mA is also included. The neuroConn trans-Direct Current Stimulator (tDCS) is a microprocessor-controlled constant current stimulator. It offers several safe and reliable stimulation modes that can be programmed.

In addition the neuroConn system offers extra software options including an advanced sham feature allowing double blind trials and a SIMPLE mode that restricts the use of the stimulator allowing the user to only choose from 4 predefined settings.

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neuroCare DC-Stimulator Brochure

neuroCare tDCS application

neuroConn tDCS Effectiveness Studies

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TriggerBox / TriggerBox Extension

The TriggerBox helps to handle and merge triggers arriving from different sources, which is quite often a requirement in complex laboratory setups.

TriggerBox

  • TriggerBox has connectors for parallel/LPT as well as BNC inputs; the latter are all isolated from each other as well as from the other input connectors.
    It is equipped with 8 toggle switches to regulate bit-wise which input should determine the value of the output parallel port, where the EEG amplifier is connected.
  • It can provide connection to the 16th bit of the BrainAmp trigger input, via an optical fibre cable or BNC connector.
  • It offers a stretching function for the 8th and 16th bits which is useful if the incoming TTL pulses are too short for the amplifier and would otherwise go undetected.
  • It is powered by USB.
  • New as of revision 2 – TriggerBox is now even more flexible and provides a virtual serial port via USB that can be directly addressed from your stimulus presentation software.

TriggerBox Extension

  • TriggerBox Extension offers 8 additional BNC connectors which can be linked to the 8 upper bits (from lines 8 and 15) of the BrainAmp or used as a standalone solution for amplifiers such as actiCHamp or V-Amp in situations where stretching, switching and isolation functions are not required.
  • It can be connected to the output trigger port of the actiCHamp in order to lead the outgoing signal to the BNC ports.

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SyncBox Brain Products Website

Press Release: TriggerBox 2 – millisecond precise trigger without a parallel port

 

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SyncBox

SyncBox is a must-have solution to boost data quality for concurrent EEG and fMRI recordings

The Syncbox is a unique tool which significantly reduces timing related errors and boosts the quality of MRI artifact correction by synchronizing the clock of the BrainAmp MR / BrainAmp MR plus amplifier with the clock driving the MRI scanner’s gradient switching system.

The SyncBox is essential to recording high quality EEG data in the MR environment and is it compatible with all major commercial MRI scanners available on the market.

  • Synchronizes the clock of BrainAmp MR amplifiers with the master clock driving the MRI scanner’s gradient system
  • Significantly reduces timing related errors and boosts the quality of gradient artifact correction
  • SyncBox scanner interface and scanner clock output are physically connected (using galvanic coupling) to avoid potential influence on the MR scanner system
  • Seamless integration with BrainVision Recorder and Analyzer software by means of dedicated trigger codes and implemented algorithms

Syncbox

Reference: Mandelkow, H., Halder, P., Boesiger, P., & Brandeis, D. (2006). Synchronization facilitates removal of MRI artefacts from concurrent EEG recordings and increases usable bandwidth. Neuroimage, 32(3), 1120-1126. https://doi.org/10.1016/j.neuroimage.2006.04.231

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SyncBox – Brain Products website

EEG-fMRI Booklet

 

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BrainVision RecView

Software for real-time data analyses

BrainVision RecView is an advanced solution designed for real-time analysis of data received over the Ethernet network via TCP-IP directly from BrainVision Recorder.

  • Widely used in the EEG/fMRI field to remove both the gradient and the ballistocardiogram artifact (permitting experimental control during the scan).
  • The “Template Drift Compensation” algorithm remedies template jitter caused by imperfect synchronization between the EEG amplifier and the scanner clocks and thus ensures optimal data correction at any time.
  • Uses the same history tree concept already implemented in BrainVision Analyzer
  • Can also be used for FFT analysis, data filtering, mapping of the surface potentials as well as BCI and bio-/neurofeedback on the incoming data.

BrainVision RecView

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MOVE

Going Wireless has never been so easy

The wireless MOVE is a solution that replaces the existing cables connecting electrodes and amplifier with wireless-based communication. This solution allows the subject to move freely and makes it very suitable for use with a Brain Computer Interface (BCI), neurofeedback and motor learning.

MOVE at a glance

  • The small, lightweight transmitter and the receiver can be used with virtually any existing amplifier/electrode combination.
  • As the transmitter is not integrated into the cap, there is no risk of damaging it when cleaning the cap. Simply disconnect the transmitter and clean the cap the way you always have.
  • Each MOVE is capable of handling 64 channels; up to 5 units can be used in the same location.
  • Normal experiments become more convenient; new paradigms can be incorporated into day-to-day research.

How does it work?

The MOVE transmitter amplifies and digitizes the incoming raw analogue signal and sends it to the MOVE receiver, where the digital data is converted back to analogue. Since the amplification factor is 1:1, the existing EEG amplifier receives exactly the same data as previously. If the data is not received properly, the receiver unit will send a TTL pulse marker to the amplifier. A further marker is sent when stable and reliable data reception resumes. This feature is extremely useful during the data analysis stage; in the unlikely event of the wireless connection being interrupted during the recording, a user can still determine exactly when the problem occurred.

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EasyCap SIGGI-II

Signal Generator & Impedance Meter

SIGGI II is a laboratory tool for generating and measuring electrical signal parameters in the voltage range of typical biophysiological signals.

Functions:

The calibrated Signal Generator, issuing both built-in and recorded signals onto 1-32 channels (accompanied by a trigger signal), can be used to verify an amplifier‘s ability to correctly record amplitudes and frequencies, to visualize filter characteristics, to check linearity of DC amplifiers and to check Common Mode Rejection (CMR).

The Impedance Meter measures the impedance between 1-32 electrodes and their reference and ground electrodes. Special custom adaptors for any EEG-Recording Cap / electrode input box can be supplied. This is a comfortable way to measure impedances independent from the EEG amplifier or if there are reasons to doubt the impedance measurement routines built into the respective amplifier.

The Amplifier/Data Logger can record, amplify and store user specific signals and replay them with the Signal Generator.

The Electrode Tester measures the electrode potential of 1-32 electrodes and its changes for up to 6 hours. This unique tool is indispensable for assessing the suitability of individual electrodes for DC recordings.

SIGGI-2 EasyCap connections

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Consumables

We offer the complete range of caps and accessories from EASYCAP and a comprehensive range of electrodes, pastes/gels, sensors and accessories in the areas of sleep, neurophsyiology, neuroscience for clinical and research applications.

Consumables Preps Pastes

For more information check out our Comprehensive Catalogue

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BrainCap

Symbiotic Devices offers a comprehensive range of caps to suit most applications. In order to reach an optimal fit, a complete range of 12 different sizes is available, choose between Asia or Caucasian Cut, as well as several colours and number of contact points.

Caps are compatible with most EEG Amplifier Systems in the market as well as TMS, MEG & MRI Compatible.

BrainCap Sizes

 

Layouts:

International Layout: 10/20 System Electrodes are
distance of 10% or 20% from Cz down to the hat line.

Specialized Equidistant Layout: Electrodes are equidistant to each other via trigonometry calculation.

BrainCaps

Cap Cuts:

Both cap types, Subtemporal and SubInion, are available in two cap cuts. One cap cut provides a better fit for more oval/rectangular head shapes and is commonly used worldwide (called “Caucasian cut”).
The other one is cut for rounder head shapes and typically provides a better fit for participants from countries like e.g. Korea, China, Taiwan and Japan (called “Asia Cut”).

 

Cap Fabrics:

All caps can be made with your choice of two different types of fabric: high-precision fabric and high-comfort fabric.

High-precision fabric is of medium elasticity and has advantages in that it provides a precise reproduction of electrode positions, a longer life span and a quick drying time.

High-comfort fabric is of higher elasticity and works with a variety of head shapes. In the majority of caps, we use the high-precision fabric for adult and juvenile cap sizes and the high-comfort fabric for baby cap sizes.

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BrainAmp Standard

The BrainAmp amplifier is a compact solution for neurophysiology research, the Amp can be used along with other units within the same product range in a great range of applications. The BrainAmp is portable and can be used for standard EEG/ERP recordings as well as other types of acquisitions including mobile applications.

BrainAMP

With a 5 kHz sampling rate per channel, the BrainAmp can be used to record EEG, EOG, EMG signals as well as evoked potentials with a frequency up to 1 kHz. The 16 bit TTL trigger input allows the detection of a large number of markers from visual, accoustic, electrical, magnetic or other stimulation modalities.

The BrainAmps can be used both with passive and active electrodes offering a great degree of flexibility and is powered by a rechargeable battery, the PowerPack.

 

Other products in the BrainAMP Series:

BrainAmp DC

BrainAmp ExG

BrainAmp MR

BrainAmp MR Plus

 

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BrainAmp ExG

BrainAMP ExG

The BrainAmp ExG amplifier is a bipolar amplifier used to record EMG, ECG, EOG and polygraphic channels such as GSR (Galvanic Skin Response), acceleration, temperature and blood pulse.

The compact BrainAmp ExG amplifier (16ch) is based on the same technology and design as the entire BrainAmp family and is therefore fully compatible with all the other members of its BrainAmp siblings.
All signals can be recorded with a sampling rate up to 5000 Hz and a broad hardware bandwidth ranging from DC to 1000 Hz. The ExG was developed as an extension to all the other BrainAmp amplifiers, however it can be used as a fully independent unit.

The ExG amplifier is powered by a rechargeable battery “the PowerPack”, and can be connected to a laptop for recordings anytime anywhere.

 

Other products in the BrainAMP Series:

BrainAmp Standard

BrainAmp DC

BrainAmp MR

BrainAmp MR Plus

 

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